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KMID : 0370920080250020128
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Yeungnam Univercity Journal of Medicine
2008 Volume.25 No. 2 p.128 ~ p.133
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A Case of Pancreatic Acinar Cell Carcinoma
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Lee Hwa-Jung
Lee Won-Sik
Lee Kyoung-Hee
Choi Eun-Jung
Park Jung-Chul
Seo Hye-Jin
Sohn Kyung-Rak
Park Seung-Chan
Bae Byung-Jo
Ji Jun-Ho
Lee Jung-Lim
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Abstract
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Acinar cell carcinoma is a rare tumor that represents 1~2% of all pancreatic cancers. Clinical and radiologic findings are inconclusive in this disease. Acinar cell carcinoma is characterized by rapid progression and early metastasis, which lead to its poor prognosis. A 41-year-old man was admitted to our hospital for abdominal pain. Abdominal computed tomography (CT) and positron emission tomography-computed tomography (PET-CT) showed a splenic mass, which was being invaded by a pancreatic tail mass and which had increased 18F-fluorodeoxyglucose (FDG) uptake. Primary radical distal pancreatectomy and splenectomy were performed. Pathologic findings revealed an acinar cell carcinoma of the pancreas. The patient underwent a total gastrectomy three months later because of gastric recurrence. Four months later, multiple hepatic metastases were discovered, and the patient underwent a left hepatectomy. During treatment with capecitabine, there was no evidence of tumor progression for 14 months. We report a case of metastatic pancreatic acinar cell carcinoma, which did not progress for an extended period while the patient was being treated with capecitabine.
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KEYWORD
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Pancreas, Carcinoma, Acinar Cell, Capecitabine
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